Spatial and Temporal Mapping of Neural Activity Associated with Auditory Hallucinations

B.R. Lennox, S. Bert, G. Park, P.B. Jones, and P.G. Morris, Lancet, 1999, 353, 644.

Abstract: This study examined a 26-year-old, right-handed male that had been suffering from paranoid schizophrenia for 8 years. The patient pressed a button at the onset of a hallucination, and magnetic resonance imaging (MRI) was used to scan his brain, showing the areas of activity during his hallucinations. Results showed that activation first appeared in the right middle temporal gyrus and then extended to a wider area of the right superior temporal and left superior temporal gyri (where the hallucination is “heard”), right middle and inferior frontal gyri, right anterior cingulate, and right cuncus.